非靶向筛查技术用于食品接触用小家电的检测与评价

Non-targeted screening technology used for the detection and evaluation of small household appliance for food contact

中文关键词:  非靶向筛查  厨房电器  食品安全  毒理学关注阈值法

英文关键词:non-targeted screening technology  kitchen appliances  food safety  threshold of toxicological concern method

中文摘要:

      目的 建立一种食品接触用小家电整机筛查和评估技术。方法 模拟厨房家电制作或接触食物的使用场景, 采用气相色谱-质谱法和超高效液相色谱-四极杆-飞行时间质谱法, 构建整机非靶向筛查技术, 并应用于食品接触用家电产品: 不粘电热锅、酸奶机、折叠水壶、测温勺、咖啡机、搅拌杯和制冰机。结果 所测样品中挥发性物质均未检出; 酸奶机、折叠水壶和测温勺中检出半挥发性物质和不挥发性物质包括芥酸酰胺等20个化合物, 7种检出物包括折叠水壶中的溶剂黄56、月桂酰胺, 测温勺中的2-甲基-N-[(2-甲基丙氧基)-甲基]-2-丙烯酰胺、N-丁基苯磺酰胺、硬脂酸甲酯、3-(3,5-二叔丁基-4-羟基苯基)丙酸甲酯和3,5-二叔丁基-4-羟基苯乙酮的暴露量超过安全暴露阈值, 需引起健康风险关注。结论 本研究开发的整机筛查方法快速有效, 适用于家电产品的食品安全评价。

英文摘要:

      Objective To establish a screening and evaluation technology for food contact small household appliances. Methods The actual use scenarios of kitchen appliance for production or food contact were simulated. Gas chromatography-mass spectrometry, ultra liquid chromatography coupled with quadrupole-time of flight mass spectrometry were used to develop whole machine non-targeted screening technology. And this technology was applied to non-stick electric cookers, yogurt machines, folding kettles, temperature-sensing spoons, coffee machines, blending cups and ice maker household appliances. Results None of the volatile substances was detected in the samples. Semi-volatile substances and non-volatile substances including 20 compounds such as erucic acid amide etc. were detected in yogurt machines, folding kettles and temperature measuring spoons. The 7 kinds of detected objects included solvent yellow 56 and laurylamide in the folding kettles, 2-methyl-N-[(2-methylpropoxy)-methyl]-2-acrylamide, N-butylbenzenesulfonamide, methyl stearate, methyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl) propionate and 3,5-di- tert-butyl-4-hydroxyphenylethyl from temperature-sensing spoons exceeded safety exposure threshold, which needed to be concerned about health risks. Conclusion The method developed in this study is fast and effective, which is suitable for food safety evaluation of household appliances.