山楂、荷叶、普洱茶膳食干预对肥胖大鼠脂质代谢的影响

Effects of dietary intervention of hawthorn, lotus leaf and Pu-erh tea on lipid metabolism in obese rat

中文关键词:  脂质代谢  普洱茶  山楂  荷叶  膳食干预

英文关键词:lipid metabolism  Pu-erh tea  hawthorn  lotus leaf  dietary intervention

中文摘要:

      目的 研究山楂、荷叶、普洱茶对高脂饮食诱导的肥胖大鼠脂质代谢的影响。方法 利用斯普拉-道来氏(Sprague-Dawley, SD)雄性大鼠制作高脂饮食诱导的肥胖模型, 通过检测体重、血脂水平、肝脏系数、体脂比等生理生化指标, 观察肝脏、肾周脂肪组织病理变化, 分析山楂、荷叶、普洱茶膳食干预对脂质代谢的影响。结果 山楂、荷叶、普洱茶及复合组均能抑制大鼠体重的增长, 调节血脂水平, 同时降低肝脏指数和体脂比, 其中复合组的效果最佳; 山楂、荷叶、普洱茶单用对肥胖大鼠受损的肝脏组织、脂肪细胞改善效果欠佳, 三者联用可明显减少肝脏炎性浸润和脂肪堆积的病变情况, 有效抑制脂肪细胞数量的增多和面积的增大。结论 山楂、荷叶、普洱茶联用可有效调节肥胖大鼠脂质代谢。

英文摘要:

      Objective To study the effects of hawthorn, lotus leaf and Pu-erh tea on lipid metabolism in high-fat diet induced obesity rat. Methods Male Sprague-Dawley (SD) rats were used to make obesity model induced by high-fat diet. Body weight, blood lipid level, liver coefficient, body fat ratio and other physiological and biochemical indicators were detected, and the pathological changes of liver and perirenal adipose tissue were observed, and further analyzed the effects of dietary intervention of hawthorn, lotus leaf and Pu-erh tea on lipid metabolism. Results Hawthorn, lotus leaf, Pu-erh tea and its compound group could inhibit the weight growth of rats, regulate blood lipid level, and reduce liver index and body fat ratio, and compound group had the best effects. Hawthorn, lotus leaf, Pu-erh tea alone had poor effect on the improvement of damaged liver tissue and adipocytes in obese rats. The combination of the three could significantly reduce the inflammatory infiltration and fat accumulation of liver lesions, and effectively inhibit the increase of the number and area of adipocytes. Conclusion The combination of hawthorn, lotus leaf and Pu-erh tea can effectively regulate lipid metabolism in obese rats.