食品过敏原生物传感检测技术研究进展

Research progress on biosensing technology for detection of food allergens

中文关键词:  食品过敏  过敏原  生物传感器  检测

英文关键词:food allergy  allergen  biosensor  detection

中文摘要:

      食品过敏原已成为全球性的食品安全隐患。应对食品过敏反应最直接、有效的方法就是避免食用和接触各种含有致敏成分的食品。因此, 快速和灵敏地检测食品中过敏原对预防和控制食品过敏反应是十分重要的。食品过敏原检测主要可以分为基于核酸和蛋白质的两大类检测技术。与基于聚合酶链式反应技术、液相色谱-串联质谱法的传统检测手段相比, 生物传感技术检测平台因具有操作简单、高通量、灵敏度高、现场便携等优点, 在食品过敏原快速检测领域备受关注。本文综述了近年来食品过敏原的生物传感检测技术研究进展, 包括电化学传感器、光学传感器和其他新型传感器及其在食品过敏原检测中的应用, 并展望了生物传感技术在食品过敏原分析中面临的挑战和发展趋势。

英文摘要:

      Food allergens have become a global food safety hazard. The most direct and effective way for dealing with food allergic reaction is to avoid eating and contacting all kinds of food containing allergenic ingredients. Therefore, the development of rapid and sensitive detection method of food allergens is significant for the prevention and control of food allergic reactions. Food allergen detection can be mainly divided into two categories, including nucleic-acid and protein-based detection technology. Compared with traditional detection methods such as polymerase chain reaction and liquid chromatography-tandem mass spectrometry, biosensing detection platforms have attracted more and more attentions in the field of rapid detection of food allergens due to their advantages of simple operation, high throughput, high sensitivity, and on-site portability. This review summarized the established biosensing technology for the detection of food allergens in recent years, including electrochemical sensors, optical sensors, and other new sensors, and prospected their applications in food allergen detection. Moreover, we also explored the challenges and further prospects for biosensing technology in food allergen analysis.