食用菌中氯化石蜡的污染水平及摄入风险评估

Concentrations and risk assessment of short and medium chain chlorinated paraffins in edible fungi

中文关键词:  食用菌  氯化石蜡  浓度  同族体分布  摄入风险评估

英文关键词:edible fungi  chlorinated paraffins  concentration  homologous distribution  dietary risk assessment

中文摘要:

      目的 了解中国市场上食用菌中氯化石蜡(chlorinated paraffins, CPs)的污染状况, 为CPs的综合摄入风险评估提供科学数据。方法 采集中国市场上24种不同食用菌品种(共计79个样品)。样品经加速溶剂萃取(accelerated solvent extraction, ASE)、净化, 采用电子捕获负离子模式下气相色谱-质谱法(gas chromatography-mass spectrometry, GC-MS)检测, 分析CPs的浓度与同族体分布。结果 在不同品种的食用菌样品中, 短链氯化石蜡(short-chain chlorinated paraffins, SCCPs)干重浓度范围在92.75~3688.35 ng/g之间, 平均浓度为797.49 ng/g; 中链氯化石蜡(medium-chain chlorinated paraffins, MCCPs)干重浓度范围在未检测到(not detected, ND)~588.68 ng/g之间, 平均浓度为235.78 ng/g。SCCPs的同族体组成以C10Cl8为主, MCCPs的同族体以C14Cl8为主。线性判别分析(linear discriminant analysis, LDA)表明不同食用菌样品中的CPs的污染模式无明显差异。SCCPs和MCCPs的估计每日摄入量(estimated daily intake, EDI)平均值分别为334.67和99.01 ng/(kg·d), 由此计算的食用菌中CPs暴露边界值(margin of exposure, MOE)均大于1000。结论 食用菌样品中SCCPs和MCCPs有着相似来源, 其摄入量低于SCCPs和MCCPs间接暴露风险阈值[10和4 ng/(kg·d)], 表明食用菌中CPs对居民没有潜在的健康风险。

英文摘要:

      Objective To understand the contamination levels of chlorinated paraffins (CPs) in edible fungi from the Chinese market, and provide scientific data for the comprehensive intake risk assessment of CPs. Methods A total of 79 samples were collected from 24 kinds of different varieties of edible fungi species in the Chinese market. The samples were purified by accelerated solvent extraction (ASE), the samples were detected by gas chromatography-mass spectrometry (GC-MS) with electron capture negative ion mode to analyze the concentration of CPs and the distribution of homologues. Results Among different varieties of edible fungi samples, the concentrations of short-chain chlorinated paraffins (SCCPs) ranged from 92.75 to 3688.35 ng/g dry weight (dw), and the average concentration was 797.49 ng/g dw; the concentration of medium-chain chlorinated paraffins (MCCPs) ranged from not detected (ND) to 588.68 ng/g dw, and the average concentration was 235.78 ng/g dw. SCCPs were dominated by C10Cl8 congeners, while MCCPs were dominated by C14Cl8 congeners. The linear discriminant analysis (LDA) results indicated there was no significant difference among contamination models of CPs in distinct edible fungi. The mean estimated daily intake (EDI) of SCCPs and MCCPs were 334.67 and 99.01 ng/(kg·d), and calculated the margin of exposure (MOE) of CPs in edible fungi were all greater than 1000. Conclusion SCCPs and MCCPs in edible fungi samples have similar sources, and their intakes are lower than the indirect exposure risk thresholds of SCCPs and MCCPs [10 and 4 ng/(kg·d)], the results indicated that the intake of CPs by edible fungi do not pose a risk to the health of residents.