肠道微生物与人体健康的关系及其影响因素研究进展

Research progress on the relationship between intestinal microorganisms and human health and its influencing factors

中文关键词:  肠道微生物  生理功能  疾病  人体健康

英文关键词:intestinal microorganisms  physiological function  diseases  human health

中文摘要:

      肠道微生物是人体内最复杂和种群数量最多的微生物生态系统, 无论是健康或者疾病状态下, 人类的生理代谢特性都在时刻受到肠道菌群结构变化的影响。而肠道微生物组成和结构的变化也会影响宿主的健康, 因此肠道微生物常被认为是人体的“隐形器官”。本文综述了肠道微生物的多样性、肠道微生物的主要生理功能、肠道微生物异常与相关疾病以及影响肠道微生物的主要因素, 以期能够更好地解释肠道菌群对人体健康和疾病的重要作用, 并且为进一步理解肠道菌群与人体健康的关系提供理论基础。

英文摘要:

      Intestinal microorganisms are the most complex and abundant microbial ecosystem in human body. Human physiological and metabolic characteristics are affected by the changes of intestinal flora structure at all times, whether in health or disease. The changes in the composition and structure of intestinal microorganisms will also affect the health of the host, so intestinal microorganisms are often regarded as the “invisible organ” of the human body. This paper reviewed the diversity of intestinal microorganisms, the main physiological functions of intestinal microorganisms, intestinal microbial abnormalities and related diseases, as well as the main factors affecting intestinal microorganisms, in order to better explain the important role of intestinal flora on human health and diseases, and provide a theoretical basis for further understanding the relationship between intestinal flora and human health.