| 后生元指益生菌在发酵过程中产生的对健康有益的生物活性化合物(包括益生菌代谢物、细胞组分或它们的混合物), 如短链脂肪酸(short chain fatty acids, SCFA)、色胺、肽、磷壁酸、肽聚糖、多糖、有机酸和脂质等。本文通过重点对后生元的产生途径、生产菌、生物活性、潜在作用机制以及其在食品中的应用前景概述表明, 与益生菌相比, 后生元具有化学结构清晰、安全剂量高、保质期长等优点; 后生元具有抗炎、抑菌、免疫调节、抗氧化、抗肥胖、抗高血压、降血脂、保肝、促进伤口愈合等生物活性, 在开发新型健康功能食品方面具有广阔前景, 但其生理作用确切的机制尚未完全阐明。 |
| Postbiotics are bioactive compounds (including probiotic metabolites, cellular components, or mixtures of them) that are produced by probiotics during fermentation for the benefit of health, such as short chain fatty acids (SCFA), serotonin, peptides, teichoic acids, peptides, peptidoglycan, polysaccharides, organic acids and lipids, etc. This paper summarized the production pathway, production bacteria, biological activity, potential action mechanism and its application prospect in food. It showed that compared with probiotics, epigenetics had the advantages of clear chemical structure, high safe dose and long shelf life. Epigenetics had biological activities such as anti-inflammatory, bacteriostatic, immune regulation, anti-oxidation, anti obesity, anti hypertension, reducing blood lipid, protecting liver and promoting wound healing. It had broad prospects in the development of new healthy functional foods, but the exact mechanism of its physiological function had not been fully clarified. |
