顶空-气相色谱质谱法测定食品接触材料中18种丙烯酸酯和甲基丙烯酸酯类的迁移量

Determination of themigration amount of 18 kinds of acrylate and methacrylates in food contact materials by headspace-gas chromatography mass spectrometry

中文关键词:  迁移量  顶空-气相色谱质谱法  食品接触材料  丙烯酸酯  甲基丙烯酸酯

英文关键词:migration  headspace-gas chromatography mass spectrometry  food contact materials  acrylate  methacrylates

中文摘要:

      目的 建立顶空-气相色谱质谱法同时测定食品接触材料中18种丙烯酸酯和甲基丙烯酸酯单体迁移量的分析方法。方法 采用水、乙酸(体积分数为4%)、乙醇(体积分数为10%、20%和50%)和橄榄油浸泡食品接触材料, 将得到水性模拟物和橄榄油模拟物通过DB-WAX毛细管柱(30 m×0.25 mm, 0.25 μm)分离, 顶空进样分析, 质谱检测, 保留时间和碎片离子定性, 峰面积定量。结果 18种单体在0.05~0.5 mg/L (水性模拟物)及0.3~3.0 mg/L (橄榄油模拟物)的浓度范围内呈良好线性, 相关系数r大于0.99。本方法对水基模拟物的检出限均为0.02 mg/L, 定量限均为0.05 mg/L; 对油基食品模拟物的检出限均为0.1 mg/L, 定量限均为0.3 mg/L。加标回收率为81.1%~109%, 相对标准偏差为0.75%~9.4%。结论 该方法前处理简单、分离度好、灵敏度高, 能够满足食品接触材料中18种丙烯酸和甲基丙烯酸及其酯类单体迁移量的分析要求。

英文摘要:

      Objective To establish a method for simultaneous determination of monomer migration of 18 kinds of acrylate and methacrylate in food contact materials by headspace-gas chromatography-mass spectrometry. Methods Water, acetic acid (volume fraction: 4%), ethanol (volume fraction: 10%, 20%, 50%) and olive oil were used to impregnate the food contact material. The aqueous and olive oil mimics were separated on a DB-WAX capillary column (30 m×0.25 mm, 0.25 μm), and analyzed by headspace injection and mass spectrometry. Retention time and fragment ion were used for characterization, peak area were used for quantification. Results The 18 kinds of monomers showed good linearity in the concentration range of 0.05?0.5 mg/L (aqueous model) and 0.3?3.0 mg/L (olive oil model), and the correlation coefficient r was greater than 0.99. The limits of detection and limits of quantification were 0.02 mg/L and 0.05mg/L respectively for water-based analogs. The limits of detection and limits of quantification were 0.1 mg/L and 0.3 mg/L respectively for the oil-based food analogues. The recoveries were 81.1%?109%, and the relative standard deviations were 0.75%?9.4%. Conclusion This method has the advantages of simple pretreatment, good separation and high sensitivity, and can meet the requirements of the analysis of 18 kinds of acrylic acid and methacrylic acid and their ester monomers in food contact materials.