高内相Pickering乳液荷载生物活性物质的构建

Fabrication of high internal phase Pickering emulsion loaded with bioactive substances

中文关键词:  高内相Pickering乳液  玉米醇溶蛋白  果胶  姜黄素  流变学特性  凝胶特性

英文关键词:high internal phase Pickering emulsion  zein  pectin  curcumin  rheological properties  gel property

中文摘要:

      目的 构建稳定荷载生物活性物质的高内相Pickering乳液。方法 通过简单的反溶剂纳米沉淀法制备玉米醇溶蛋白/果胶复合颗粒, 再通过均质乳化技术, 构建荷载姜黄素的高内相Pickering乳液, 研究在不同pH条件下该乳液体系的储藏稳定性、外观、粒径和流变学特性。结果 该荷载姜黄素的高内相Pickering乳液(油相占比高达80%)能稳定储藏两个月以上不变质, 乳液粒径较小, 其流变学行为表明该乳液具有较好的粘弹性和凝胶特性, 并且随着pH值的降低, 胶体颗粒的三相接触角越接近90°, 乳液的凝胶性越强, 乳液越稳定。结论 本方法制备简单, 操作方便, 成功构建了荷载姜黄素的高内相Pickering乳液。

英文摘要:

      Objective To build a high internal phase Pickering emulsion with stable loading of bioactive substances. Methods The zein/pectin composite particles were prepared by a simple anti-solvent nano-precipitation method, and the high internal phase Pickering emulsion loaded with curcumin was constructed by homogeneous emulsification technology. The storage stability, appearance, particle size and rheological properties of the emulsion system under different pH conditions were studied. Results The high internal phase Pickering emulsion(oil phase proportion wasas high as 80%) loaded with curcumin could be stored for more than 2 months without metamorphism. The emulsion particle size was small, the rheological behavior showed that the emulsion had good viscoelastic and gel properties, and with the decrease of pH value, the three-phase antennae of colloidal particles was closerto 90°, the gelatability of emulsion was stronger, and the emulsion was more stable. Conclusion This method is simple to prepare and operate, and the high internal phase Pickering emulsion loaded curcumin is successfully constructed.