磷脂对肥胖诱导肾损伤保护作用的研究进展

Research progress of protective effects of phospholipids on obesity-induced renal injury

中文关键词:  磷脂  肥胖  肾损伤  保护作用

英文关键词:phospholipids  obesity  renal injury  protection influence

中文摘要:

      近几年来, 中国人群尤其是儿童肥胖的发生率明显上升, 随之肥胖导致的肾病引起越来越多关注, 也对其发病机制、病理特点、防治等进行了较深入的研究。除了药物疗法及形成健康的生活方式, 功能食品营养因子在缓解或防治慢性肾脏病方面也有一定应用, 尤其功能性油脂磷脂, 其具有特殊的生理功能, 作为构成所有细胞膜的基本成分, 与肾脏病相关病理活动有一定联系。本文对肥胖性肾损伤的发病机制及磷脂结构功能进行概述, 综述了磷脂对肥胖导致肾损伤的保护作用的研究, 为开发针对肥胖引起的肾功能损伤的膳食补充剂或功能性食品提供了理论基础。

英文摘要:

      In recent years, the incidence of obesity in Chinese people, especially in children, has been increasing significantly, and the renal disease caused by obesity has attracted more and more attention. The pathogenesis, pathological characteristics, prevention and treatment of the renal disease have also been deeply studied. In addition to drug therapy and the formation of a healthy lifestyle, functional food nutrition factors are also used to alleviate or prevent chronic renal disease, especially functional grease phospholipid, which have special physiological functions, and it is the basic component of all cell membranes, which is associated with pathological activities related to renal disease. In this paper, the pathogenesis of renal injury caused by obesity and structure function of phospholipids were summarized, and the protective effects of phospholipids on renal injury induced by obesity were reviewed, which provides a theoretical basis for the development of dietary supplements or functional foods for obesity-induced renal function injury.