电感耦合等离子体质谱法同时测定大枣中7种重金属及有害元素及健康风险评估

Simultaneous determination of 7 heavy metals and harmful elements in jujube by inductively coupled plasma-mass spectrometry and health risk assessment

中文关键词:  大枣  重金属  微波消解  电感耦合等离子体质谱法  健康风险评估

英文关键词:jujube  heavy metals  microwave digestion  inductively coupled plasma-mass spectrometry  health risk assessment

中文摘要:

      目的 建立电感耦合等离子体质谱法测定大枣中7种重金属及有害元素含量的方法并开展健康风险评估。方法 采用微波消解法进行样品前处理、电感耦合等离子体质谱法测定。健康风险评估模型计算风险评估模型(target hazard quotients, THQ)。结果 各元素在相应范围内线性良好(r＞0.999), 仪器精密度良好(RSD＜5%, n=6), 各元素加样回收率为83.93%~104.95%。3个产地不同批次大枣中铜(Cu)、砷(As)、镉(Cd)、汞(Hg)、铅(Pb)重金属及有害元素含量较低, 低于《中华人民共和国药典》2020年版中指导值; 以THQ作为风险评估指标时, 大枣所含重金属含量对人体健康无风险。结论 ICP-MS法灵敏、准确, 可用于红枣中7种重金属含量的测定。

英文摘要:

      Objective To establish a method for the determination of 7 heavy metals and hazardous elements in jujube by inductively coupled plasma-mass spectrometry (ICP-MS) and carry out health risk assessment. Methods Samples were pretreated by microwave digestion, and determined by ICP-MS. The target hazard quotients (THQ) was calculated by health risk assessment model. Results The linear range of the elements was good (r>0.999), the precision of the instrument was good (RSD<5%, n=6), and the recoveries of the elements were 83.93%-104.95%. The content of Cu, As, Cd, Hg, Pb in different batches of jujube in the 3 origins was lower, which was lower than the guidance of the pharmacopeia of the People's republic of China value. When THQ was used as a risk assessment indicator, the heavy metal content in jujube had no risk to human health. Conclusion The ICP-MS method is sensitive and accurate, and is feasible for 7 heavy metals content determination in jujube.