白蜂蜡对维生素D3含量的影响研究

Influence of beeswax on the vitamin D3 content

中文关键词:  白蜂蜡  维生素D3  软胶囊  稳定性

英文关键词:beeswax  vitamin D3  soft capsule  stability

中文摘要:

      目的 研究软胶囊内容物中添加白蜂蜡对维生素D3的含量影响。方法 设计方案, 白蜂蜡比例分别为0%和1.5%, 在考察3个月后分别检测不同方案中维生素D3的含量, 找出添加白蜂蜡对维生素D3含量的影响关系。结果 配方中不添加白蜂蜡时, 加速3个月后维生素D3含量降幅仅4.7%。白蜂蜡添加比例为1.5%时, 加速3个月后维生素D3含量降幅为73.4%。结论 添加白蜂蜡会导致软胶囊内容物中的维生素D3含量降解。故在设计产品配方时, 应留意避免这2种成分同时使用, 以免发生配伍反应。

英文摘要:

      Objective To study the effect of beeswax on the content of vitamin D3 in soft capsules. Methods Experiments that 0% or 1.5% proportion of beeswax were designed and carried out and samples were investigated. Contents of vitamin D3 in different schemes were detected after three months of investigation to find out the influence of beeswax on the content of vitamin D3. Results Without beeswax in the formula, the content of vitamin D3 only decreased by 4.7% after three months accelerated investigation. When the proportion of beeswax was 1.5%, the content of vitamin D3 decreased by 73.4% after three months accelerated investigation. Conlusion Beeswax can degrade the content of vitamin D3 in contents of soft capsules. Therefore, in the design of product formula, attention should be paid to avoid the use of two ingredients at the same time, so as to avoid compatibility reaction.