圆苞车前子壳复配粉剂的通便功能研究

Research on the defecation function of hypocotyls of Plantago rotundus compound powder

中文关键词:  圆苞车前子壳  当归提取物  低聚木糖  通便  小鼠

英文关键词:hypocotyls of Plantago rotundus  Angelica sinensis extract  xylooligosaccharides  defecation  mice

中文摘要:

      目的 研究圆苞车前子壳复配粉剂的通便功能。方法 按照《保健食品检验与评价技术规范》(2003版)中通便作用检验方法, 对通便粉剂的通便功能进行研究。经口分别以408、815和1630 mg/(kg?BW)剂量的受试物对小鼠灌胃, 7 d后测定其排首粒黑便时间、小肠墨汁推进率、6 h内排粪便重量和粪便粒数。结果 与空白对照组相比, 便秘模型对照组、各剂量组小鼠体重均无显著性差异(P>0.05)。与便秘模型组比较, 各剂量组小鼠小肠墨汁推进率显著增加(P<0.05), 首次排黑便时间明显缩短(P<0.01), 6 h内排黑便粒数和重量显著增加(P<0.01)。结论 以圆苞车前子壳、当归提取物、低聚木糖为主复配的粉剂具有改善小鼠通便作用的功效。

英文摘要:

      Objective To investigate the defecation function of hypocotyls of Plantago rotundus compound powder. Methods The defecation function of defecation powder was studied according to the test method of Technical Standards for Testing & Assessment of Health Food (2003). Mice were orally administered with 408, 815, and 1630 mg/(kg?BW) of defecation powder respectively, and the time of first black stool excretion, the ink propelling rate in small intestine, the weight of fecal excretion and the number of fecal particles within 6 h were determined after seven days. Results Compared with the blank control group, there was no significant difference in body weight among all the testing groups (P>0.05). Compared with the model group, the pushing rate of ink propelling in small intestine in each dose group was significantly increased (P<0.05), the time of first black stool excretion was significantly decreased (P<0.01), and the quantity and weight the black stool within 6 h were significantly increased (P<0.01). Conclusion The extract of Hypocotyls of Plantago rotundus, Angelica sinensis, and xylooligosaccharides has defecation function in mice.