免疫营养在COVID-19综合治疗中的辅助作用与应用前景

Adjuvant role and application prospects of immunonutrition in the comprehensive treatment of COVID-19

中文关键词:  冠状病毒  SARS-CoV-2  COVID-19  炎症  免疫营养

英文关键词:coronavirus  SARS-CoV-2  COVID-19  inflammation  immunonutrition

中文摘要:

      目前, 由新型冠状病毒SARS-CoV-2引起的新型冠状病毒肺炎(Corona Virus Disease 2019, COVID-19)大流行已在全球蔓延。除了隔离之外, 迫切需要采取能够降低感染和死亡风险的公共卫生措施。营养不良和导致患者免疫功能低下的各种非传染性基础疾病(如肥胖症、糖尿病、心血管疾病等)是重症COVID-19的重要危险因素。应用免疫营养手段, 补充具有药理学作用的特殊营养素, 以特定方式刺激免疫细胞, 增强免疫应答功能, 维持适度的免疫反应, 调整细胞因子的产生和释放, 减轻有害或过度炎症反应, 对COVID-19患者预后具有积极意义。本文就维生素、矿物元素、多不饱和脂肪酸、膳食纤维等免疫营养素在降低呼吸道感染风险中的作用, 以及免疫营养在COVID-19中应用现状进行综述, 以期为免疫营养在COVID-19综合治疗中的辅助作用提供参考依据。

英文摘要:

      The world is in the grip of the COVID-19 caused by SARS-Cov-2pandemic. Public health measures that can reduce the risk of infection and death in addition to quarantines are desperately needed. Malnutrition and various non-communicable underlying diseases, such as obesity, diabetes mellitus, cardiovascular diseases, leading to immunodeficiency in patients are important risk factors for severe COVID-19. Special nutrient supplement have pharmacological effect, stimulate the immune cells in a particular way, strengthen the function of immune response, maintain appropriate immune response, adjustment of cytokine production and release, reduce harmful or excessive inflammation, have positive sense to the prognosis of patients with COVID-19. This article reviewed the role of immune nutrients such as vitamins, mineral elements, polyunsaturated fatty acids, dietary fiber in reducing the risk of respiratory tract infections, as well as the current application of immunonutrition in COVID-19, in order to provide reliable reference for the adjuvant role of immunonutrition in the comprehensive treatment of COVID-19.