微量元素与早产婴幼儿生长发育的相关性

Research progress on the correlation between trace elements and growth and development of premature infants

中文关键词:  微量元素  早产婴幼儿  生长发育

英文关键词:trace elements  premature infants  growth and development

中文摘要:

      早产是新生儿和5岁以下儿童死亡的主要原因, 同时作为一种常见的临床不良妊娠结局, 不仅增加了母婴短期和长期并发症的风险, 而且给个人、家庭和社会造成巨大负担, 其发病原因及机制较为复杂, 其中母体血液微量元素变化对胎儿发育有着非常重要的影响, 微量元素的不平衡, 可能导致不良妊娠结局。关于微量元素对早产婴幼儿的作用研究甚少, 故本文结合近些年国内外关于微量元素应用的研究, 综述了微量元素(铁、铜、锌、硒、锰5种)与早产婴幼儿生长发育的关系, 以及微量元素影响早产发生的作用机制(炎症反应、氧化应激、内分泌调节机制), 以期为微量元素在早产婴幼儿的生长发育研究中提供一定的理论指导依据。

英文摘要:

      Preterm birth is the main cause of death of newborn and children under 5 years old. At the same time, as a kind of common clinical adverse pregnancy outcomes, it not only increases the risk of maternal and infant short-term and long-term complications, but alao poses a great burden to individuals, families and society. Its etiology and mechanism are more complex, and the changes of maternal blood trace elements changes have a very important impact on fetal development. The imbalance of trace elements may lead to adverse pregnancy outcomes. There are few researches on the effect of trace elements on premature infants. Combined with the research on trace elements application at home and abroad in recent years, this paper reviewed the relationship between trace elements (iron, copper, zinc, selenium, manganese) and the growth and development of premature infant, and the mechanism of trace elements affecting the occurrence of preterm birth (inflammation, oxidative stress, endocrine regulation mechanism), in order to provide some theoretical guidance for the study of trace elements effect in the preterm infant's growth.