基因芯片法在食源性疾病中诊断效果及影响多因素Logistic分析研究

Study on the diagnostic effect of gene chip in foodborne diseases and Logistic analysis of multiple factors

中文关键词:  基因芯片  食源性疾病  诊断效果  影响因素  Logistic分析

英文关键词:gene chip  foodborne illness  diagnostic effect  influencing factors  logistic analysis

中文摘要:

      目的 对比基因芯片法在食源性疾病诊断中的效果, 并对影响多因素进行logistic分析。方法 选择180例临床表现符合食源性疾病诊断标准的患者作为研究对象, 随机均分为实验组和对照组各90例, 对照组采用传统的常规培养检测方法, 实验组采用基因芯片法进行检测, 对比2种方法的检出率、检测耗时以及检测灵敏度。结果 实验组的检出率和检测灵敏度均高于对照组的检出率和检测灵敏度, 对照组的检测耗时大约是实验组检测耗时的8.24倍。结论 相比常规方法, 应用基因芯片法的诊断速度更快、准确率更高, 在诊断食源性疾病中的应用效果更佳。通过对单因素的?2和t检验, 确定对食源性疾病有直接影响的多个因素。对影响食源性疾病的多个因素进行Logistic分析, 分析结果表明在本次研究分析中, 影响较大的因素是人们的饮食卫生以及进食规律。

英文摘要:

      Objective To compare the effect of gene chip method in the diagnosis of foodborne diseases, and to carry out Logistic analysis on the influencing factors. Methods Choose 180 cases of patients with clinical manifestations of foodborne disease diagnosis standard as the research object, randomly divided into experimental group and the control group (n=90), the control group used the traditional regular train detection method, the experimental group used gene chip testing. The detection rate of two methods, detection time consuming and the detection sensitivity were compared. Results The detection rate and detection sensitivity of the experimental group were higher than that of the control group, and the detection time of the control group was 8.24 times longer than that of the experimental group. Conclusion Compared with conventional methods, the method of gene chip is faster and more accurate in diagnosing foodborne diseases. Multiple factors directly affecting foodborne illness are identified by single factor's ?2 and t tests. Logistic analysis was carried out on several factors affecting foodborne diseases, and the analysis results showed that in this study, the major factors influencing the analysis were people's dietary hygiene and eating habits.