B族维生素泡腾片中微生物限度方法的研究

Study on the method of microbial limit in B group vitamins effervescent tablets

中文关键词:  B族维生素泡腾片  微生物限度检查法  薄膜过滤法

英文关键词:B vitamins effervescent tablets  microbial limit test  membrane-filter procedure

中文摘要:

      目的 开发检测B族维生素泡腾片的微生物限度检查新方法。方法 通过物理去除样品抑菌性的方法检测B族维生素泡腾片的微生物, 通过实验组、供试品对照组、菌液对照组对薄膜过滤法的检测方法进行方法适用性试验。结果 实验组菌落数减去供试品对照组菌落数的值与菌液对照组菌落数的比值均在0.5~2范围内。结论 此法操作简单、科学、准确, 可用于B族维生素泡腾片的微生物检查。

英文摘要:

      Objective To develop a new method of microbial limit test for B vitamins effervescent tablets. Methods The microorganism of B vitamins effervescent tablets was detected by physical removal bacteriostasis of the samples. In this verification experiment, the applicability of the membrane-filter procedurewas tested by the experimental group, the test product control group and the bacterial liquid control group. Results The ratio between the bacterial colony number in the experimental group minus the bacterial colony number in the test product control group and the bacterial colony number in the liquid control group was all within the range of 0.5 to 2. Conclusion This method is simple, scientific and accurate, and can be used for microbial examination of B vitamins effervescent tablets.