液相色谱质谱法测定马口铁涂层中三聚氰胺迁移量不确定度的评定

Uncertainty evaluation in determination of melamine migration in tinplate coating by liquid chromatography-mass spectrometry

中文关键词:  马口铁涂层  三聚氰胺  迁移量  不确定度  液相色谱质谱法

英文关键词:tinplate coating  melamine  migration  uncertainty  liquid chromatography-mass spectrometry

中文摘要:

      目的 评定液相色谱质谱法测定马口铁涂层中三聚氰胺迁移量的不确定度。方法 采用液相色谱质谱法测定马口铁涂层中三聚氰胺迁移量, 建立数学模型。根据不确定度评定相关规则和标准对实验过程中的不确定度因素包括重复性、标准溶液配制、仪器校准、标准曲线拟合、浸泡面积、浸泡体积等进行不确定度评定。结果 当50%(V:V) 乙醇溶液中三聚氰胺迁移量为0.038 mg/kg时, 其扩展不确定度为0.007 mg/kg (P=95%, k=2)。结论 马口铁涂层中三聚氰胺迁移量的不确定度主要来源有重复性测定、标准溶液配制和标准曲线拟合。

英文摘要:

      Objective To evaluate the uncertainty in determination of melamine migration in tinplate coating by liquid chromatography-mass spectrometry. Methods Liquid chromatography-mass spectrometry was used to determine the amount of melamine migration in the coating of tinplate, and a mathematical model was established. According to relevant rules and standards for uncertainty evaluation, the uncertainty was evaluated including repeatability, standard solution preparation, instrument calibration, standard curve fitting, soaking area, soaking volume, etc. Results When the migration amount of melamine in 50% (V:V) ethanol solution was 0.038 mg/kg, the expanded uncertainty was 0.007 mg/kg (P=95%,k=2). Conclusion The uncertainty of melamine migration in tinplate coating mainly comes from repeatability, standard solution preparation and standard curve fitting.