微波消解-电感耦合等离子体质谱法测定衢枳壳中17种微量元素的含量

Determination of 17 trace elements in Qu aurantii fructus by microwave digestion-inductively coupled plasma mass spectrometry

中文关键词:  电感耦合等离子体质谱法  衢枳壳  元素

英文关键词:inductively coupled plasma mass spectrometry  Qu aurantii fructus  elements

中文摘要:

      目的 建立微波消解-电感耦合等离子体原子发射光谱-质谱法测定衢枳壳药材中17种元素的分析方法。方法 采用微波消解进行前处理, 电感耦合等离子体原子发射光谱-质谱联用技术结合内标元素校正基体抑制效应, 外标法定量。结果 在0.5~500 μg/L的浓度范围内, 各元素有良好的线性关系, 相关系数均大于0.999。各元素的检出限为2 ng/L~1 μg/L, 加标回收率为67.3%~109%, 相对标准偏差均小于15%。结论 本研究建立的方法准确、可靠、灵敏度高, 适用于衢枳壳基质中多元素测定。

英文摘要:

      Objective To establish a method for the determination of 17 elements in Quzhou fructus aurantii by microwave digestion-inductively coupled plasma atomic emission spectrometry-mass spectrometry. Methods Based on microwave digestion as pre-treatment, the samples were detected by inductively coupled plasma atomic emission spectrometry-mass spectrometer, adjusted system shift and matrix depression by internal standard element and quantified by external standard method. Results In the concentration range of 0.5?500 μg/L, each element had a good linear relationship, and the correlation coefficients were greater than 0.999. The limits of detection of each element were 2 ng/L?1 μg/L. The recoveries were 67.3%?109%, and relative standard deviations were less than 15%. Conclusion This method is accurate, reliable and sensitive, suitable for the quantitative determination of elements in Chinese traditional medicine Qu aurantii fructus.