气相色谱-质谱法测定柑橘中丙溴磷的不确定度评定

Uncertainty evaluation for the determination of profenofos in citrus by gas chromatography-tandem mass spectrometry

中文关键词:  不确定度  气相色谱-质谱法  丙溴磷  柑橘

英文关键词:uncertainty  gas chromatography-tandem mass spectrometry  profenofos  citrus

中文摘要:

      目的 建立气相色谱-质谱法(gas chromatography-tandem mass spectrometry, GC-MS/MS)测定柑橘中丙溴磷不确定度的评定模型。方法 根据CNAS-GL006:2018《化学分析中不确定度的评估指南》, 分析气相色谱-质谱法测定柑橘中丙溴磷的不确定度来源, 建立科学的数学模型并量化各个影响分量, 得到丙溴磷测定结果的拓展不确定度。结果 气相色谱-质谱法测定丙溴磷时, 对于结果的不确定度影响顺序为: 标准曲线的稀释配制过程＞线性拟合＞样品的前处理过程, 当柑橘中丙溴磷含量为0.15 mg/kg时, 其拓展不确定度为0.04 mg/kg(k=2)。结论 该评估模型为气相色谱-质谱法测定丙溴磷, 内标法进行定量时的不确定度的评估提供了参考依据。

英文摘要:

      Objective To establish a evaluation model of uncertainty for determination of profenofos in citrus by gas chromatography-tandem mass spectrometry (GC-MS/MS). Methods According to the CNAS-GL006:2018 Evaluation guide for uncertainty in chemical analysis, the source of uncertainty for determination of phosphorus bromide in citrus by gas chromatography-mass spectrometry was analyzed, and a scientific mathematical model was established to quantify the influence components. Results The order of influence of uncertainty on the result of determination of profenofos by GC-MS/MS was as follow: The dilution preparation process of the standard curve> linear fitting>the pre-treatment process of sample. When the content of profenofos in citrus was 0.15 mg/kg, the extension uncertainty was 0.04 mg/kg (k=2). Conclusion The evaluation model provides a reference for the evaluation of uncertainty in quantitative analysis in the determination of profenofos by GC-MS/MS.