食品接触材料中全氟化合物的迁移规律研究

Study on the migration of perfluorinated compounds in food contact materials

中文关键词:  全氟化合物  食品接触材料  全氟新烷磺酸  全氟辛酸  迁移规律  膳食暴露

英文关键词:perfluorinated compound  food contact material  perfluoronova alkane sulfonic acid  perfluorooctanoic acid  migration rule  dietary exposure

中文摘要:

      目的 研究全氟化合物从食品接触材料到食品模拟物中的迁移规律。方法 根据全氟化合物制品在日常生活中的使用情况, 选择4个品牌的纸杯和3个品牌的包装袋进行了试验, 以全氟辛酸、全氟辛烷磺酸等为研究对象, 参考食品接触材料及制品迁移试验通则的具体要求, 采用不同食品模拟物、不同操作方式、不同保存时间和温度等因素考察对全氟新烷磺酸、全氟辛酸的迁移量和迁移规律的影响。目标化合物通过C18色谱柱进行分离, 以乙腈-5 mmol/L的乙酸铵为流动相进行梯度洗脱; 流速0.2 mL/min; 柱温为30 ℃; 进样量1 μL, 由三重四级杆质谱进行定性和定量分析。结果 数据显示在模拟物为食用油时PFOA的迁移量是最大的, 超过0.01 ng/cm2; 其他情况PFOA的溶出量都低于0.002 ng/cm2; PFOS的溶出量均较少, 低于0.002 ng/cm2。结论 初步得到食品接触材料中典型全氟化合物的迁移规律基础数据, 说明无论是何种品牌的纸杯或是包装袋, 接触食物均会产生PFOA和PFOS的微量溶出, 经过膳食暴露可能会引起健康危害。

英文摘要:

      Objective To study the migration of perfluorinated compounds from food contact materials to food simulants. Methods According to the use of perfluorochemical products in daily life, 4 brands of paper cups and 3 brands of package bags were selected for testing. Perfluorooctanoic acid and perfluorooctane sulfonic acid were taken as the research objects, and the specific requirements of the general rules for the migration of food contact materials and products were referred. The effects of different food simulants, different operation methods, different storage time and temperature on the migration quantity and migration rule of perfluorooctanoic acid and perfluorooctanoic acid were investigated. The target compounds were separated by C18 column and eluted with acetonitrile-5 mmol/L ammonium acetate as the mobile phase, the flow rate was 0.2 mL/min, the column temperature was 30 ℃, the injection volume was 1 μL, and the triple quadrupole mass spectrometry was performed for qualitative and quantitative analysis. Results The data showed that the migration of PFOA was the most when the simulant was edible oil, exceeding 0.01 ng/cm2. In other cases, the leaching amount of PFOA was less than 0.002 ng/cm2. The leaching amount of PFOS was less than 0.002 ng/cm2. Conclusion This paper preliminarily obtain the basic data of the migration law of typical perfluorinated compounds in food contact materials, indicating that no matter what brand of paper cups or packaging bags, PFOA and PFOS microdissolution could be generated after food contact, and the dietary exposure might cause health hazards.