一种具有抑菌作用漱口水的工艺研究

Study on technology of a kind of mouthwash with bacteriostatic effect

中文关键词:  金银花  茶叶  抑菌作用  漱口水

英文关键词:honeysuckle  tea  bacteriostatic effect  mouthwash

中文摘要:

      目的 研究了一种具有清洁口腔及抑菌等作用漱口水的工艺。方法 首先,以金银花及茶叶为主要原料,通过水提法提取其中有效成分,并采用体外抑菌试验来评价其抑菌作用。然后,通过优化两者复配,确定其最佳配比。在此基础上,以色、香及味为评价指标,通过单因素试验,确定金银花和茶叶混合液、柠檬酸、薄荷油、甜菊糖、甘油、乙醇及食盐的添加量。最后,通过正交试验,确定了产品的最佳配方。结果 产品最佳配方：金银花和茶叶混合液(250 mg/mL金银花与250 mg/mL茶叶1:1组成)7%、乙醇10%、甘油10%、柠檬酸0.05%、薄荷油0.1%、甜菊糖0.05%、食盐1%、去离子水72.79%。结论 该漱口水可清除口腔异味及清新口气,且可对常见口腔炎症有一定辅助治疗作用。

英文摘要:

      Objective The technology of a kind of oral mouthwash with cleaning mouth and bacteriostatic effects was investigated. Methods Firstly, honeysuckle and tea as main raw materials, the active ingredients in the raw materials were extracted by water, and the bacteriostatic effect of the raw materials was evaluated by in vitro bacteriostatic assays. Furthermore, in order to optimize the ratio of main raw materials, the bacteriostatic effect of the two main raw materials was explored in a series of experiments. On this basis, in term of color, aroma and taste, the optimal addition of honeysuckle and tea mixture, citric acid, peppermint oil, stevia, glycerin, ethanol and salt was determined in single factor tests. In addition, an orthogonal experiment was carried out to determine the optimal formula. Results The optimal formulas showed as follows: honeysuckle and tea mixture (250 mg/mL honeysuckle and 250 mg/mL tea 1:1 composition) 7%, ethanol 10%, glycerol 10%, citric acid 0.05%, peppermint oil 0.1%, chamomile sugar 0.05%, salt 1.0% and deionized water 72.79%. Conclusion The mouthwash can remove bad breath and freshen breath, and be used as an adjuvant treatment for common oral inflammation.