饮食疗法对癌症病人血液中微量元素指标变化的影响分析

Effect of Dietary Therapy on the Changes of Trace Elements in Blood of Cancer PatientsLuodan Linya

中文关键词:  饮食疗法  癌症  微量元素

英文关键词:diet therapy  cancer  trace elements

中文摘要:

      【】目的：本研究旨在分析探究饮食疗法对癌症病人血液中微量元素指标变化的影响。方法：收集2013年5月至2015年6月我院收治的180例恶性肿瘤患者,将其随机分为研究组与对照组,研究组(n=96)患者由专业营养师根据饮食调查与各项检查结果给予饮食治疗,而对照组(n=84)患者则根据饮食指导自行控制饮食。同期收集40例于我院体检的健康人群作为健康对照组。对比治疗前、后癌症患者血清中铁(Fe)、铜(Cu)、硒(Se)、锌(Zn)等微量元素水平变化情况。结果：癌症组患者的Cu、Zn元素浓度明显高于健康对照组,而Fe、Se明显低于健康对照组(P＜0.05)。不同癌症患者与健康对照组相比,肝癌患者的Cu与Zn低于健康对照组,而Se则高于健康对照组(P＜0.05)；胃癌患者的Fe低于健康对照组；结直肠癌患者的Fe和Cu均高于健康对照组,而Zn低于健康对照组(P＜0.05)；乳腺癌患者的Fe、Se、Zn均低于健康对照组,而Cu高于健康对照组(P＜0.05)；肺癌患者的Fe、Se均低于健康对照组,而Se高于健康对照组(P＜0.05)。治疗前,两组患者的Fe、Cu、Se、Zn浓度经比较无明显差异(P＞0.05),但在治疗后,研究组患者Fe、Cu、Se、Zn浓度的改善情况明显优于对照组患者(P＜0.05),差异显著。结论：血液中铁、铜、硒、锌等微量元素水平与癌症的发生密切相关,而饮食疗法能有效控制癌症患者血液中相关微量元素水平。

英文摘要:

      【】Objective: This study aimed to analyze the effect of dietary therapy on the changes of trace elements in blood of cancer patients. Methods: 180 patients with malignant tumors admitted to our hospital from May 2013 to June 2015 were randomly divided into study group and control group. The study group (n=96) was given diet therapy by a professional dietitian based on dietary surveys and various examination results, while the control group (n=84) received self-control diet according to dietary guidelines. In the same period, 40 healthy people in our hospital were collected as healthy controls. The levels of trace elements such as iron (Fe), copper (Cu), selenium (Se) and zinc (Zn) in serum of patients with cancer before and after treatment were compared. Results: The concentrations of Cu and Zn in the cancer group were significantly higher than those in the healthy control group, while Fe and Se were significantly lower than those in the healthy control group (P<0.05). Compared with healthy controls, patients with different cancers had lower Cu and Zn than healthy controls, while Se was higher than healthy controls (P<0.05). The cancer of patients with gastric cancer is lower than that of the healthy control group; Fe and Cu in patients with colorectal cancer were higher than those in healthy controls, while Zn was lower than healthy controls (P<0.05). Fe, Se, and Zn in breast cancer patients were lower than those in healthy controls, while Cu was higher than healthy controls (P<0.05). Fe and Se in lung cancer patients were lower than those in healthy controls, and Se was higher than healthy controls (P<0.05). Before treatment, the concentrations of Fe, Cu, Se and Zn in the two groups were not significantly different (P>0.05). However, after treatment, the improvement of Fe, Cu, Se, Zn concentration in the study group was significantly better than that of the control group (P<0.05), and the difference was significant. Conclusion: The levels of trace elements such as iron, copper, selenium and zinc in the blood are closely related to the occurrence of cancer, and diet therapy can effectively control the levels of related trace elements in the blood of cancer patients.