羊胎盘复合物对老年小鼠抗氧化作用的研究

Antioxidant effects of composite extraction of goat placental preparations on aged mice

中文关键词:  羊胎盘  抗氧化  丙二醛  蛋白质羰基  超氧化物岐化酶  谷胱甘肽

英文关键词:goat placental preparations  antioxidant  malondialdehyde  protein carbonyl  superoxide dismutase  glutathione

中文摘要:

      目的 评价羊胎盘复合物的抗氧化作用。方法 ICR老年小鼠, 分别以0.45、0.90和2.70 g/kg剂量连续灌胃30 d后, 检测血液丙二醛(malondialdehyde, MDA)、蛋白质羰基、超氧化物岐化酶(superoxide dismutase, SOD)和还原性谷胱甘肽(glutathione, GSH)等指标评价其抗氧化功能。结果 老年小鼠经口给予羊胎盘复合物30 d后, 羊胎盘复合物能减少血液MDA的含量, 升高GSH和SOD的含量。结论 结果显示, 羊胎盘复合物对老年小鼠显示了一定的抗氧化作用。

英文摘要:

      Objective To evaluate the antioxidant effects of composite extraction of goat placental preparations. Methods ICR aged mice were consistently administered intragastricly with the composite extraction (0.45, 0.90 and 2.70 g/kg) for 30 days. Subsequently, function indexes including malondialdehyde (MDA), protein carbonyl, superoxide dismutase (SOD) and glutathione (GSH) were detected. Results After oral administration of composite extraction of goat placental preparations in aged mice for 30 d, the content of MDA was decreased, and the content of GSH and SOD were increased. Conclusion The results show that the composite extraction of goat placental preparations can enhance the antioxidant function of aged mice.