茶叶活性成分的抗炎作用及其机制研究进展

Research progress in anti-inflammatory effects of tea active ingredients and its mechanisms

中文关键词:  茶多酚  表没食子儿茶素没食子酸酯  炎症因子  信号通路

英文关键词:tea polyphenol  epigallocatechin gallate  inflammatory cytokines  signaling pathways

中文摘要:

      茶叶中主要活性成分如茶多酚、茶氨酸、茶黄素具有较好的抗炎作用, 且茶多酚效果最佳。虽然茶多酚的抗氧化作用被世界公认, 但这并不是其发挥抗炎作用的唯一机制, 其机制应与抑制炎症因子、调节相关炎症信号通路、抗氧化等综合作用有关。本文综述了茶叶及茶叶成分茶多酚、茶氨酸、茶黄素的抗炎作用及其机制, 其中重点阐述了主要儿茶素组分表没食子儿茶素没食子酸酯(epigallocatechin gallate, EGCG)的抗炎机制, 为茶叶抗炎作用的深入研究提供参考, 为健康饮茶和茶叶抗炎功能产品的研发提供理论依据。

英文摘要:

      The main active components in tea, such as tea polyphenols, theanine and theaflavins, have good anti-inflammatory effects, and tea polyphenols have the best effect. However, antioxidant properties may not be the sole mechanism of anti-inflammatory. The mechanisms of anti-inflammatory are related with the comprehensive work of inhibiting inflammatory factor, modulate inflammatory signaling pathways, antioxidant, etc. This paper reviewed the anti-inflammatory effects of the main active components in tea and its mechanisms, and mainly emphasized the anti-inflammatory mechanism of catechin component epigallocatechin gallate (EGCG). It provided references for further study on the anti-inflammatory effects of tea, and a theoretical basis for the research and development of healthy tea drinking and tea anti-inflammatory products.