电化学传感技术在羟基多环芳烃检测中的应用

Application of electrochemical sensing technology in detection of hydroxyl polycyclic aromatic hydrocarbons

中文关键词:  羟基多环芳烃  电化学传感技术  生物标志物

英文关键词:hydroxyl polycyclic aromatic hydrocarbons  electrochemical sensing  biomarkers

中文摘要:

      羟基多环芳烃(hydroxyl polycyclic aromatic hydrocarbons, OH-PAHs)是多环芳烃(polycyclic aromatic hydrocarbons, PAHs)在人体和动物体内代谢生成的一类羟基化合物。通常采用尿液中OH-PAHs作为生物标志物来综合评价人体对多环芳烃的内暴露情况。常见的OH-PAHs分析方法主要有色谱法、同步荧光光谱法、毛细管电泳法以及酶联免疫分析法等。近来, OH-PAHs分析的目光开始转向电分析化学技术。本文介绍OH-PAHs检测的意义以及电化学传感技术在OH-PAHs检测中的应用, 重点论述PAHs生物标志物、富集传感条件的选择以及对同步检测多种OH-PAHs可能性的探究, 并对此种检测方法的发展趋势进行展望。

英文摘要:

      Hydroxyl polycyclic aromatic hydrocarbons (OH-PAHs) are a group of hydroxyl metabolites of polycyclic aromatic hydrocarbons (PAHs) in human and animal. They can be used as the biomarkers to evaluate the inner exposure level of PAHs for human. The common detection methods of OH-PAHs include chromato-graphy, synchronous fluorescence spectrometry, capillary electrophoresis, and enzyme linked immunoassay, etc. However, the analysis of OH-PAHs recently begins to turn to electrochemical analysis. In this article, the significance and electrochemical sensing technology in the detection of OH-PAHs were introduced, the biomarkers of PAHs, the selection of the enrichment sensing conditions and the possibility of simultaneous detection of various OH-PAHs were mainly discussed. And the expected advances for the coming years were also predicted.