同位素稀释三重串联四级杆质谱法测定饮用水中4种增塑剂

Determination of 4 plasticizers in drinking water by isotope dilution triple quadrupole mass spectrometry

中文关键词:  饮用水  同位素稀释  气相色谱-三重四级杆质谱法  增塑剂

英文关键词:drinking water  isotope dilution  gas chromatography coupled with triple quadrupole mass spectrometry  plasticizers

中文摘要:

      目的 建立同位素稀释-气相色谱-三重四级杆质谱法同时测定饮用水中3种邻苯二甲酸酯和己二酸二(2乙基己基)酯的方法。方法 样品采用正己烷提取后, 气相色谱三重四极杆质谱检测, 内标法定量。结果 方法具有良好线性, 相关系数R均大于0.998, 定量限为0.1~0.5 g/L。各组分平均回收率为92.3%~105.3%, 相对标准偏差为0.4 %~5.5%。实际样品中3种增塑剂有检出。结论 该方法操作简单, 准确度和灵敏度高, 重现性好, 可作为生活饮用水中增塑剂含量检测的确证方法。

英文摘要:

      Objective To develop a method for the simultaneous determination of 4 plasticizers in drinking water by isotope dilution-gas chromatography coupled with triple quadrupole mass spectrometry (GC-MS/MS). Methods Four plasticizers in the tested sample were extracted with n-hexane. The extraction was determined by GC-MS/MS, using internal standard method. Results The correlation coefficients (R) of 4 plasticizers were over 0.998, the limits of quantitation for 4 plasticizers were 0.1~0.5 g/L. The average recoveries of 4 plasticizers in drinking water were ranged from 92.3 % to 105.3 %. In addition, the relative standard deviations (RSDs) were in the range of 0.4%~5.5 %. Conclusion The method has advantages of simplicity, sensitivity and repeatability, and is suitable for the analysis of phthalate acid esters in drinking water.