乳清蛋白水解制备功能性多肽的研究概况

Research progress on preparing functional polypeptide from whey protein hydrolysis

中文关键词:  乳清蛋白  功能性多肽  生物学功能

英文关键词:whey protein  bioactive peptides  bioactivity

中文摘要:

      乳清是生产干酪及干酪素过程中获得的大量液态副产物, 含有丰富的营养成分, 其主要成分乳清蛋白的营养价值极高。随着近年来小肽生物活性功能研究的开展, 对于乳清蛋白水解物中功能性多肽的研究成为主要方向。近年来的研究中发现乳清蛋白中含有多种生物活性肽, 包括ACE抑制肽、抑菌肽、抗病毒肽、抗氧化活性肽及其它活性肽。目前, 国内外有关ACE抑制肽的研究较多, 而对降胆固醇肽的研究多是以大豆蛋白为原料, 而更具有研究价值的乳清蛋白源降胆固醇肽研究较少。本人以乳清蛋白为原料, 对其酶解产物的降胆固醇活性肽进行分离制备, 既充分利用了干酪的副产物, 减少了资源浪费和环境污染, 又能提供一种新型降胆固醇功能产品, 为商业化开发乳清蛋白降胆固醇功能产品提供理论依据。本文结合本人对降胆固醇肽的研究, 综述了乳清蛋白源功能性多肽的制备、分离纯化技术及其活性多肽的研究概况。

英文摘要:

      With the development of research on biological activity of small peptides in recent years, research on functions of whey protein hydrolysate peptides become hot. Whey is a liquid by-product obtained in the process of cheese and casein. Whey is rich in nutrients, and its main component is whey protein which has a high nutritional value. Recent studies have found that whey protein contains a variety of bioactive peptides, including antihypertensive peptides, antimicrobial peptides, antiviral peptide, antioxidant activity peptides and other bioactive peptides, and has been a hot research. At present, there are many studies on the antihypertensive peptides at home and abroad, and there are fewer studies on hypocholesterolemic peptides. Most of studies about hypocholesterolemic peptides are about soy protein. However, whey protein hypocholesterolemic peptides have more research value, in fact. In this experiment, whey protein was as raw material, hypocholesterolemic peptides were separated and prepared from its hydrolysates. In this subject, by-product of cheese was full used, it not only reduced waste of resources and environmental pollution, but also provided a theoretical basis for the commercial development of hypocholesterolemic functional products. This paper reviews the whey protein source of functional polypeptides preparation, separation and purification technology and research status of active peptides.