保健食品中邻苯二甲酸二异辛酯快速筛查的 定性定量分析方法

The method of rapid screening, qualitative and quantitative analysis for diisooctyl phthalat in health food

中文关键词:  邻苯二甲酸二异辛酯  气相色谱-质谱联用法  快速筛查方法  保健食品  定性定量分析

英文关键词:diisooctyl phthalate  gas chromatography-mass spectrometry (GC-MS)  fast screening method  health food  qualitative and quantitative analysis

中文摘要:

      目的 建立保健食品中邻苯二甲酸二异辛酯(diisooctyl phthalate, DEHP)快速筛查的定性定量分析方法。方法 样品经无水乙醇超声提取后, 采用气相色谱-质谱联用法在选择离子扫描模式下进行定量检测。结果 DEHP在0.01070~10.70 μg/mL 范围内具有良好的线性关系, 相关系数为0.9987, 该方法检出限(LOD)为0.02 μg/g, 定量限(LOQ)为0.07 μg/g。加标回收率为73.8%~96.8%; 结论 该法简便、快速、准确, 溶剂用量少, 可用于保健食品中DEHP的检测。

英文摘要:

      Objective To develop a gas chromatograph-mass spectrometry method for rapid screening, qualitative and quantitative analysis of diisooctyl phthalat in health food. Methods Samples were ultrasonically extracted by ethanol and analyzed by LC-MS/MS. Mass data acquisition was conducted under selected ion scan mode. Results The method showed a good linearity in the range of 0.01070~10.70 μg/mL (r>0.9987) for diisooctyl phthalats. The limit of detection of this method was 0.02 μg/g (S/N=3). The limit of quantitative of this method was 0.07 μg/g (S/N=10). The recoveries were 73.8%~96.8%. Conclusion This method is convenient, fast, accurate, reliable to operate, and it is suitable for the determination of diisooctyl phthalat in health food.