方便面、大米和花椒中环氧乙烷、2-氯乙醇、二氧六环和环氧丙烷残留量的测定

Determination of ethylene oxide, 2-chloroethanol, dioxide and propylene oxide residues in instant noodle, rice and pepper

中文关键词:  环氧乙烷  2-氯乙醇  二氧六环  环氧丙烷

英文关键词:ethylene oxide  2-chloroethanol  dioxide  propylene oxide

中文摘要:

      目的 建立QuEChERS-气相色谱-三重四极杆质谱法测定方便面、大米和花椒中环氧乙烷、2-氯乙醇、二氧六环和环氧丙烷的残留量的方法。方法 样品经粉碎后用乙腈提取, 提取液经分散固相萃取净化, 分流进样, DB-WAX毛细管色谱柱分离, 多反应监测模式检测, 外标法定量。结果 各化合物在10~500 μg/L范围内线性关系良好, 相关系数r2均大于0.99; 环氧乙烷、2-氯乙醇、二氧六环和环氧丙烷检出限均为0.01 mg/kg, 定量限均为0.02 mg/kg; 环氧乙烷、2-氯乙醇、二氧六环和环氧丙烷的回收率范围分别为77.2%~111.8%、86.5%~114.1%、89.2%~114.0%、83.0%~108.6%, 相对标准偏差分别为2.2%~11.3%、1.9%~11.4%、3.0%~11.9%、2.5%~11.7%。结论 该方法操作简单、分析速度快、结果准确, 可用于方便面、大米和花椒中环氧乙烷、2-氯乙醇、二氧六环和环氧丙烷残留量的测定。

英文摘要:

      Objective To establish a method for determination of the amount of ethylene oxide, 2-chloroethanol, dioxide and propylene oxide in instant noodle, rice and pepper by QuEChERS-gas chromatography-triple quadrupole mass spectrometry. Methods Samples were extracted by acetonitrile, purified by dispersed solid phase extraction, divided into samples, separated by DB-WAX capillary column, detected by multiple reaction monitoring mode, and quantified by external standard. Results Each compound showed a good linear relationship in the range of 10–500 μg/L, the correlation coefficient r2 was greater than 0.99; the limits of detection for ethylene oxide, 2-chloroethanol, dioxide and propylene oxide were 0.01 mg/kg, the limits of quantification were 0.02 mg/kg; the recovery rates of ethylene oxide, 2-chloride ethanol, dioxide and propylene oxide ranged from 77.2%–111.8%, 86.5%–114.1%, 89.2%–114.0%, 83.0%–108.6%, respectively, the relative standard deviations were 2.2%–11.3%、1.9%–11.4%、3.0%–11.9%, and 2.5%–11.7%, respectively. Conclusion This method has simple operation steps, rapid analysis speed and accurate results. It can be used for the determination of ethylene oxide, 2-chlorine ethanol, dioxide and propylene oxide in instant noodle, rice and pepper.