基于金属纳米团簇的荧光传感器在食品安全检测中的应用研究进展

Research progress in the application of metal nanoclusters in food safety detection

中文关键词:  金属纳米团簇  荧光传感器  食源性致病菌  抗生素残留  重金属离子

英文关键词:metal nanoclusters  fluorescent sensor  foodborne pathogenic bacteria  antibiotic residues  heavy metal ions

中文摘要:

      食品安全事件频繁发生, 给人类健康造成了极大的威胁和危害, 为保证食品的品质与安全, 建立灵敏、准确、快速、简单易操作的检测方法尤为重要。金属纳米团簇作为一种荧光纳米材料, 具有光稳定性、生物相容性、低毒性等优点, 已被广泛应用于细胞标记、生物成像、分析检测等领域。以食源性致病菌、抗生素残留、重金属离子3种广泛存在且毒性较大的食品污染物为例, 本文概述了荧光金属纳米团簇在食品安全检测中的应用, 包括不同荧光金属纳米团簇的制备方法、对目标物的传感机制、传感器的性能等内容, 重点介绍了金属纳米团簇与目标分析物间的相互作用机制, 以期为食品中污染物荧光检测法的构建提供一定的理论基础, 同时为进一步拓展金属纳米团簇在食品分析检测领域的应用提供新的思路。

英文摘要:

      Food safety has become a major global concern due to the frequent occurrence of food poisoning incidents, which have caused great threat and harm to the public health. Therefore, in order to ensure the quality and safety of food, it is necessary to establish sensing methods of sensitive, accurate, fast and easy to operate. As a fluorescent nanomaterial, metal nanoclusters have advantages of photostability, biocompatibility, and low toxicity, and have been widely used in cell labeling, biological imaging, and analytical sensing, etc. Taking foodborne pathogens, antibiotic residues and heavy metal ions as examples, this paper summarized the application of fluorescent metal nanoclusters in food safety detection, including the preparation methods of different fluorescent metal nanoclusters, the sensing mechanism of the target object, and the performance of the sensors, emphatically introduced the interaction mechanism between the target analyte and metal nanoclusters. In order to provide a certain theoretical basis for the construction of fluorescence detection of contaminants in food, and further expand the application of metal nanoclusters in the field of food analysis and detection.