超级微波消解-串联四极杆电感耦合等离子体质谱法测定当归中27种无机元素

Determination of 27 kinds of inorganic elements in Angelica sinensis by super microwave digestion-tandem quadrupole inductively coupled plasma mass spectrometry

中文关键词:  当归  无机元素  串联四极杆电感耦合等离子体质谱法  超级微波化学平台

英文关键词:Angelica sinensis  inorganic elements  tandem quadrupole inductively coupled plasma mass spectrometry  super microwave chemistry platform

中文摘要:

      目的 建立超级微波消解-串联四极杆电感耦合等离子体质谱法(tandem quadrupole inductively coupled plasma mass spectrometry, ICP-MS/MS)测定当归中27种无机元素含量的分析方法。方法 以当归为材料, 通过优化消解酸体系与超级消解平台工作参数进行试样消解, 在线引入500 μg/L混合内标以校正信号漂移。在等离子气流速为15.0 L/min、辅助气流速为0.9 L/min、功率为1550 W时, 采用ICP-MS/MS测定试样中27种无机元素的含量。结果 所测27种元素线性关系良好, 相关系数在0.9993~1.0000之间, 检出限为0.00003~0.13548 mg/kg, 定量限为0.00010~0.40643 mg/kg, 回收率为93.90%~115.40%, 精密度在0.02%~2.55%之间; 国家标准物质-黄芪的测定结果均在推荐值范围以内。结论 该方法操作简单、灵敏度高, 适用于当归中27种无机元素含量的测定。

英文摘要:

      Objective To establish an analytical method for the determination of 27 kinds of inorganic elements in Angelica sinensis by super microwave digestion-tandem quadrupole inductively coupled plasma mass spectrometry (ICP-MS/MS). Methods Using Angelica sinensis as the material, the samples were digested by optimizing the digestion acid system and the working parameters of the super digestion platform, and the signal drift was corrected by introducing a 500 μg/L mixed internal standard online. The content of 27 kinds of inorganic elements in samples were determined by ICP-MS/MS when the flow rate of plasma gas was 15.0 L/min, the flow rate of auxiliary gas was 0.9 L/min, and the power was 1550 W. Results The linear relationships of the 27 kinds of elements were good, with the correlation coefficient between 0.9993 and 1.0000, the detection limits between 0.00003 and 0.13548 mg/kg, and the limits of quantitation between 0.00010 and 0.40643 mg/kg. The recoveries were 93.90%-115.40%, and the precision were 0.02%-2.55%; the results of the determination of the national standard substance-Astragalus membranaceus were within the recommended values. Conclusion This method is simple and sensitive, and is suitable for the determination of 27 kinds of inorganic elements in Angelica sinensis.