黄芪中皂苷类成分的研究进展

Research progress of saponins in Astragalus membranaceus

中文关键词:  黄芪  皂苷类化合物  提取方法  分离纯化  含量测定

英文关键词:Astragalus membranaceus  saponins  extraction method  separation and purification  content determination

中文摘要:

      黄芪为蒙古黄芪或膜荚黄芪的干燥根, 是中医临床上常用的大宗中药材, 在食品、保健品、化妆品等行业具有广泛的应用前景。黄芪属于中国传统中草药中的补虚类药, 其味甘性微温, 归属脾肺经, 具有广泛的药用价值, 很多具有保健功能的口服液中均含有黄芪, 有学者将黄芪等中药材添加到鸡汤中研究其保健功能。黄芪中主要含有皂苷类、多糖类、黄酮类、氨基酸及微量元素等化学成分, 黄芪皂苷是黄芪中主要的有效成分, 从黄芪中分离出来的皂苷类化合物达50多种。黄芪皂苷的提取及分离纯化是以黄芪皂苷类成分作为指标成分进行黄芪药材及饮片质量评价的关键环节, 合适的提取、分离纯化及含量测定方法对黄芪的开发与综合利用具有重要意义。本文主要综述了黄芪皂苷类成分的提取、分离纯化、含量测定等, 以期为黄芪的进一步开发与利用提供一定的参考依据。

英文摘要:

      Astragalus membranaceus is the dried root of Astragalus mongolicus or Astragalus membranaceus, which is commonly used as a bulk Chinese medicinal material in clinical practice. It has a wide application prospect in food, health care products, cosmetics and other industries. Astragalus membranaceus is a kind of medicine in traditional Chinese herbal medicine to replenish deficiency. It has a sweet and mild taste, belongs to spleen and lung meridian, and has a wide range of medicinal value, many oral liquids with health care functions contain astragalus. Some scholars have added astragalus and other Chinese medicinal materials into chicken soup to study its health care functions. Astragalus membranaceus mainly contains saponins, polysaccharides, flavonoids, amino acids, trace elements and other chemical components. Astragalus saponins are the main active components of Astragalus membranaceus, and more than 50 saponins have been isolated from Astragalus membranaceus. The extraction, separation and purification of Astragalus saponinarekey steps to evaluate the quality of Astragalus medicinal materials and decoction pieces with Astragalus saponin as the index component. Appropriate extraction, separation, purification and content determination methods are of great significance to the development and comprehensive utilization of Astragalus. This paper reviewed the extraction, purification and content determination of Astragalus saponins, in order to provide some references for the further development and utilization of Astragalus.