离子色谱-串联质谱法测定生活饮用水中的高氯酸盐、氯酸盐和溴酸盐

Determination of perchlorate, chlorate and bromate in drinking water by ion chromatography- tandem mass spectrometry

中文关键词:  离子色谱-串联质谱法  生活饮用水  高氯酸盐  氯酸盐  溴酸盐

英文关键词:ion chromatography-tandem mass spectrometry  drinking water  perchlorate  chlorate  bromate

中文摘要:

      目的 建立离子色谱-串联质谱法同时测定生活饮用水中高氯酸盐、氯酸盐和溴酸盐含量的分析方法。方法 选用高容量、亲水性IonPacAS-20阴离子交换柱为分析柱对高氯酸盐、氯酸盐和溴酸盐进行分离, 以淋洗液自动发生器在线产生KOH为淋洗液进行洗脱。采用外接水模式, 串联质谱进行检测。采用电喷雾离子源负离子模式和多反应监测测定, 外标法定量。结果 高氯酸盐、氯酸盐和溴酸盐的线性范围分别为0.04~20.00 μg/L, 0.02~10.00 μg/L, 0.04~20.00 μg/L, 相关系数r2>0.999, 检出限分别为0.02、0.01和0.02 μg/L, 定量限分别为0.04、0.02和0.04 μg/L, 加标回收率在90.0%~98.8%, 相对标准偏差(relative standard deviation, RSD)小于8.0%。结论 该方法简便、可靠、稳定、灵敏度高, 可用于生活饮用水中高氯酸盐、氯酸盐和溴酸盐含量的快速测定与确认。

英文摘要:

      Objective To establish a method for simultaneous determination of perchlorate, chlorate and bromate in drinking water by ion chromatography-electrospray tandem massspectrometry (IC-MS/MS). Methods Perchlorate, chlorate and bromate were separated on a highcapacity, hydrophile IonPacAS-20 analysis column by elution with KOH eluent generated from an eluent generator cartridge (EGC). External water mode and tandem mass spectrometry were used for detection.Multiple reaction monitoring mode andnegative ion mode of electrospray ion were carried out for determination and quantitative determination was performed by the external standards. Results The calibration curves of perchlorate, chlorate andbromate were linear in the ranges of 0.04~20.00, 0.02~10.00, 0.0420.00μg/L, respectively, with correlation coefficient r2 more than 0.999. The limist of detection of perchlorate, chlorate and bromated were 0.02, 0.01, 0.02 μg/L, and the limits of quantitation were 0.04, 0.02, 0.04 μg/L, respectively. The recoveries of perchlorate, chlorate and bromate were in the range of 90.0%98.8%, with relative standard deviation (RSD) less than 8.0%.Conclusion This method is simple, reliable, stable, sensitive and can be used for the determination of perchlorate, chlorate and bromate in drinking water.