转录组学在乳酸菌研究中的应用

Application of transcriptomics in the research of lactic acid bacteria

中文关键词:  乳酸菌  转录组学  测序  应用

英文关键词:lactic acid bacteria  transcriptomics  sequencing  application

中文摘要:

      转录组学是一门从RNA水平上研究基因表达情况的学科, 是一种重要的生命科学研究手段, 被广泛应用到多个物种的研究中。乳酸菌作为一类公认安全的食品工业微生物, 在发酵食品工业中发挥着重要作用。随着乳酸菌分子水平研究的快速发展, 乳酸菌转录组学日益成为研究热点。本文对转录组学及其研究技术进行综述, 阐述了转录组学在研究乳酸菌生长代谢调控机制、环境胁迫应激反应、发酵及益生功能中的应用, 并对乳酸菌转录组学研究存在的问题及发展趋势进行了讨论, 期望为乳酸菌转录组学研究提供参考。

英文摘要:

      Transcriptomics is a subject that studies gene expression at the RNA level, which is an important method of life science and is widely used in the study of many species. Lactic acid bacteria, generally regarded as safe microorganisms, play a vital role in fermented food industry. As the development of genetic level study on lactic acid bacteria, the transcriptomics of lactic acid bacteria has become a hot topic. This paper summarized the transcriptomics and its research techniques, described the application of the transcriptomics in the study of growth and metabolism regulation mechanisms, stress responses to environmental stress, fermentation and probiotic functions of lactic acid bacteria, and discussed the problems and the future of the transcriptomics of lactic acid bacteria, in order to provide information for the research of the transcriptomics of lactic acid bacteria.