我国天然产物绿原酸活性及提取工艺研究进展

Research progress of the activity and extraction process of the natural product of chlorogenic acid in China

中文关键词:  绿原酸  活性  提取工艺  研究进展

英文关键词:chlorogenic acid  activity  extraction process  research progress

中文摘要:

      绿原酸是一种重要的植物次生代谢产物, 目前对其活性的研究已深入到食品、保健、医药和日用化工等多个领域。针对近年来国内对绿原酸研究的相关报道, 本文综述了天然产物绿原酸的活性研究进展, 如抑制和激活相关酶的活性, 抗氧化活性及作用机制, 抑制突变和抗肿瘤活性, 对细胞的促进凋亡或增强保护活性, 抑菌活性及抗病毒活性, 降血脂及调节机体血脂代谢作用活性等方面的研究。同时, 本文围绕超声波法、微波法、酶法、混合辅助提取法、超临界提取法等常规处理方法, 对于绿原酸的提取工艺和提取方法方面的研究进展的相关报道也进行了总结。此外, 本文也对今后的绿原酸活性研究与提取工艺进行了一定的展望。

英文摘要:

      Chlorogenic acid is a kind of important plant secondary metabolites, and its activity research has been deeply into the food, health care, medicine and daily chemical industry and other fields. This paper reviewed the activity research progress of chlorogenic acid in domestic reports of recent years, such as inhibition and activation related enzyme activity, antioxidant activity and mechanism, mutation suppression and antitumor activity, promotion of cell apoptosis or enhancement of protection activity, antibacterial activity and antiviral activity, reducing blood fat and regulation of the body's blood lipid metabolism activity. At the same time, the related reports of extraction process and methods of chlorogenic acid were summarized, including ultrasonic method, microwave method, enzymatic method, mixing assisted extraction and supercritical fluid extraction. In addition, this article also prospected the future research on activity and extraction technology of chlorogenic acid.